Rose composed a number of variations on his own stage adjustment of the teleplay.
Remarkable rights to the film were offered and numerous versions based on the movie were staged in Europe in 1958, including an adaptation by Andre Obey in Paris. 
In 1964, Leo Genn appeared in the London production, directed by Margaret Webster. For other theatrical adjustments, wherein female actors are cast, the play is often retitled 12 Angry Individuals.
Harold Pinter directed a production of the play, which opened at the Bristol Old Vic on March 7, 1996.  With set design by Eileen Diss, lighting style by Mick Hughes, and outfit design by Tom Rand, its cast consisted of Stuart Rayner (Juror 1, Supervisor), Kevin Dignam (Juror 2), Tony Haygarth (Juror 3), Timothy West (Juror 4), Maurice Kaufmann (Juror 5), Douglas McFerran (Juror 6), Tim Healy (Juror 7), Kevin Whately (Juror 8), Alan MacNaughtan (Juror 9), Peter Vaughan (Juror 10), Robert East (Juror 11), Christopher Simon (Juror 12), Joshua Losey (Guard), and E. G. Marshall, as the Voice of the Judge.  (Marshall had represented “# 4” in Sidney Lumet’s 1957 movie variation of the play.).
In 2003, the British producer/director Guy Masterson directed an all comic revival  at the Assembly Rooms consisting of Bill Bailey as Juror 4, Phil Nichol as Juror 10, Owen O’Neill as Juror 8, Stephen Frost as Juror 3 and Russell Hunter as Juror 9 throughout the Edinburgh Fringe Festival which broke the existing ticket office record for drama at the Fringe Celebration and garnered much important honor. 
The Roundabout Theatre Business presented a Broadway production of the play in 2004, starring Boyd Gaines as a more combative Juror 8, with James Rebhorn (Juror 4), Philip Bosco (Juror 3), and Robert Prosky as the Voice of the Judge. (Prosky had starred as “# 3” in a Washington D.C. production of the show, opposite Roy Scheider as “# 8” and Rene Auberjonois as “# 5”.).
In 2005, the British producer/director Man Masterson directed a hugely effective Australian variation of his hit Edinburgh 2003 production produced by Arts Projects Australia and Adrian Bohm  at QPAC Brisbane, Sydney Theatre and Melbourne Athenaeum consisting of Shane Bourne as Juror 3, Peter Phelps as Juror 4, Marcus Graham as Juror 8, George Kapiniaris as Juror 2 and Henri Szeps as Juror 9.  This production won three Melbourne Green Space Awards and an election for “Best Play” at the Helpmann Awards.
In 2007, L.A. Theatre Works presented a production of the play that was recorded as an audiobook; directed by John de Lancie, the cast included Dan Castellaneta, Jeffrey Donovan, Héctor Elizondo, Robert Foxworth, James Gleason, Kevin Kilner, Richard Kind, Alan Mandell, Rob Nagle, Armin Shimerman, Joe Spano, and Steve Vinovich. 
The London West End production opened in November 2013 (running until March 1, 2014) at the Garrick Theatre. Directed by Christopher Haydon, the cast consisted of Martin Shaw, Robert Vaughn, Jeff Fahey, Nick Moran, Robert Blythe, Miles Richardson and Martin Turner. 
In 2014, Independent Theatre Pakistan carried out an adjustment of this play at Alhamra Arts Council, Lahore, directed by Azeem Hamid.